Cushings Syndrome - Symptom, Causes, Treatment of Cushings Syndrome
Cushings Syndrome may also
from long-term high-dose care with cortico steroid drugs.
when the body's tissues are
levels of cortisol for long periods of time. A lot of people
the symptoms of Cushing's syndrome because they take glucocorticoid hormones such as prednisone for asthma, rheumatoid arthritis, lupus or other
Symptom of Cushings Syndrome
Symptom of cushings syndrome include fat deposits
the face neck and trunk; weariness; muscular weakness; salt and water retention; acne;
bruising; menstlruall irregularities; and signs (in women) of virilisation, such as
of the voice,
in body, shape, loss of scalp hair, and
in facial and body hair. Complications of cushings syndrome include
blood pressure, The symptoms and signs of cushings syndrome induced by a chronic
of corticosteroid hormones in the blood. The
by a tumour of the outer part (cortex) of the adrenal gland, or may be
to over inspiration of the adrenal glands by a tumour the pituitary gland.
Many children and teenagers with Cushing's syndrome will
of the following:
- extreme weight gain
- growth retardation
- missed periods in teenage girls
- excess hair growth
- reddish-blue streaks on the skin
- high blood pressure
- tiredness and weakness
- either very early or late puberty
Adults with the disease may also have symptoms of
hair growth, high blood pressure, and skin
difficulties. In addition, they may show:
- muscle and bone weakness
- moodiness, irritability, or depression
- sleep disturbances
- high blood sugar
- menstrual disorders in women and
fertility in men
Causes of Cushings Syndrome
Cushing's syndrome is the term
the clinical effects of
glucocorticoid action on the body. Cushing's syndrome can
- A person
hormones for a
time as treatment for
some other disorder or disease, for
instance, taking a steroidal anti-inflammatory for arthritis.
- The body
too much cortisol. Too much cortisol is
when the pituitary and adrenal glands are not working in
the right way. This can be induced by:
- A noncancerous tumor of the pituitary gland which
amounts of the hormone adrenocorticotropin (ACTH). This, in turn,
the adrenal glands to
too much cortisol. This form of Cushing's syndrome is
as "Cushing's disease."
kinds of cancerous tumors in
parts of the body can
the adrenal glands to generate extra cortisol.
on the adrenal glands, which may or may not be cancerous, can
the adrenal glands to
Treatment of Cushings Syndrome
Treatment of cushings syndrome is by castigation of the under lying cause. Treatments for Cushing's syndrome are
your body's cortisol production to normal. By
indurate, or even
lowering cortisol levels, you'll
improvements in your signs and symptoms. Left untreated, however, Cushing's syndrome can
to death. The treatment choice depend on the cause. For example:
- If a tumour in an adrenal gland is the reason, an operation to withdraw it will cure the condition.
- For adrenal hyperplasia, both adrenal glands may require to be
withdraw. You will then require to take lifelong replacement therapy of several adrenal hormones.
- Other tumours in the body that produce 'ectopic' ACTH may be able to be removed, depending on the kind of tumour, where it is, etc.
- Medication to block the production or
of cortisol may be an choice.
How is Cushing's syndrome diagnosed?
of the patient's medical history, somatic examination and laboratory tests.
x-ray exams of the adrenal or pituitary glands are beneficial for locating tumors. These tests
if excess levels of cortisol are