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Glomerulonephritis - Symptom, Causes, Treatment of Glomerulonephritis


Glomerulonephritis is the irritation of the glomeruli, the permeating units of the kidney. Establish in the cortex (outer part) of the kidney, glomeruli are microscopic cups which filter out fluid and fritter products from the blood which flows by the capillaries inside them. If the glomeruli transform inflamed, they are incapable to work effectively, and they provide the loss of proteins fromthe blood into the urine.

Glomerulonephritis (that used to be known as Bright's disease) may be acute or chronic, and can give rise to a lot's of symptoms depending on the extent and rate of progress of the soreness.

Causes of Glomerulonephritis

Glomerulonephritis can refine inevitable bacterial, viral or parasitic infections, specially streptococcal infection of the throat or upper airways in children and young adults. Antigens (proteins which induce antibody production) on the surface of infecting organisms reason an immune response which usually overcomes the infection. But if resistant complexes (antigen-anti-body combinations) are deposited in the glomerular capillaries, glomerulonephritis produce.

This disorder may also acquire in diseases such as systemic LUPUS ERY HEMATOSIS, some cancers and blood disorders and as a reaction to certain drugs or poisons.

Symptoms of Glomerulonephritis

Glomerulonephritis which produce from an infection develops 1 to 6 weeks later on its onset. The rate of onset and increase of'symptoms are very changeable.

Approximately half of all patients sustain no symptoms, and the situation is discovered by chance when the urine is examined for several other causes. Symptoms which may appear include puffiness of the face ( particularly close to the eyes) which may be followed by more general OEDEMA (accumulation of immoderate fluid in tissues) decreased urine production dark or smoky urine (due to leakage of red blood cells by the glomeruli), headache, and occasionally blunt pain in the loins.

Diagnosis of Glomerulonephritis

If glomerulonephritis is pretend, the diagnosis can be sustained by urine and blood tests; sometimes kidney biopsy is required.

Treatment of Glomerulonephritis

Except for gentle cases, admission to hospital is suggested. Treatment rely on the cause and rigidity of kidney damage and includes rest, antibiotics or antiparasitic drugs if confiscate ORTICOSTEROID DRUGS to decrease irritation. IMMUNOSUPPRESSANT DRUGS, and in severe cases PLASMAPHERESIS to displace harmful immune complexes from the blood, if kidney failure produce, DLALYSIS (artificial filtering of waste products from the blood) may be essential.

Out look of Glomerulonephritis

Most children who produce gentle glomerulonephritis, later on streptococcal infection recover from, it adequately. In more life-threatening cases of glomerulonephritis' from any cause, there may be a rapid or gradual progression to KIDNEY FAILURE, and ongoing dialysis or kidney transplant will be required.

 

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