Acrodermatitis Chronica Atrophicans - Symptoms & Treatment
Acrodermatitis chronica atrophicans is a skin rash denotative of the third or late stage of European Lyme borreliosis. ACA is a dermatological condition that takes a chronically progressive course and lastly leads to a widespread atrophy of the skin. Involvement of the peripheral nervous system is frequently observed, particularly polyneuropathy. This progressive skin procedure is because of the effect of continuing active infection with the spirochete Borrelia afzelii. B afzelii is the major pathophysiology, but may not be the special, etiologic agent of ACA.
ACA shows atrophy of collagen and elastic tissue as well as hypertrophic basophilic elastic tissue; whereas in morphea, sclerosis and polarizing flexible tissue are major. The acute inflammatory stage of ACA is treated sufficiently. The therapeutic result is difficult to appraise in patients with the chronic atrophic phase, in which many changes are only partly reversible. Treatment consists of antibiotics include doxycycline and penicillin for up to four weeks in the acute case.
Causes of Acrodermatitis Chronica Atrophicans
Absence of correct treatment of early Lyme borreliosiscan develop acrodermatitis chronica atrophicans.
Symptoms of Acrodermatitis Chronica Atrophicans
Some sign and symptoms related to Acrodermatitis Chronica Atrophicans are as follows:
- A progressive dermatitis appear on the feet, hands, elbows, other knees, composed of hardened erythematous plaques that become atrophic, giving a tissue-paper look to the affected areas.
- Cutaneous plaque on the sole.
Treatment for Acrodermatitis Chronica Atrophicans
- Penicillin G-- Beta-lactam antibiotic.
- Leukocytoclastic vasculitis other vessel occlusion may be seen in a few cases.
- Burgdorferi flagellum a needed allusion antigen for increasing routine serology in Lyme borreliosis.
- Ceftriaxone -- Bactericidal against Borrelia species.
- Acrodermatitis Chronica Atrophicans is recommended if the level of specific antibodies is low. It should take for 3 weeks.