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Angiolymphoid Hyperplasia with Eosinophilia - Symptoms & Treatment


Angiolymphoid hyperplasia with eosinophilia is an ostensibly non-malignant, locally proliferating lesion composed of channels of small blood vessels surrounded by lymphocytes and eosinophils (these are two types of white blood cell). In Kimura's illness the lesions are deeper-seated, with no first overlying skin lesions. In angiolymphoid hyperplasia with eosinophilia the lesions are smaller and characterised by thick-walled alleged histiocytoid other epithelioid blood vessels. Angiolymphoid hyperplasia with eosinophilia has been reported from many parts of the globe but appears to be specifically general in Japan.

Causes of Angiolymphoid Hyperplasia with Eosinophilia

Some causes & risk factors of Angiolymphoid Hyperplasia with Eosinophilia are as follows:

  • The main cause is the infiltration of inflammatory cell.
  • Sometimes reaction in the skin or neoplastic disease can lead to this disease.
  • Another cause may be the presence of lymphoid follicles with germinal centers.

Symptoms of Angiolymphoid Hyperplasia with Eosinophilia

Main symptom is pain and unusual pulsation and bleeding.

Angiolymphoid Hyperplasia with Eosinophilia Treatment

  • Medication such as intralesional injections of glucocorticoids, topical imiquimod, interferon alpha-2a, cytotoxic agents may be used to treat the disease but are not very effective.
  • Surgical methods such as Mohs micrographic surgery, cryotherapy, pulsed-dye laser etc can be used but recurrence of the disease is possible.

 

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