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Epidermolysis Bullosa - Symptoms & Treatment


Epidermolysis bullosa is a scarce hereditary disorder which causes blistering of the tissues of the skin in answer to a minor damage. This is generally observed in kids and can be minor other much more serious which is very different case by case. The kids who have this disorder are often called by several various names such as butterfly children (because their skin is as brittle as a butterfly’s wings) and Cotton Wool Babies. The condition of the kids can get gradually worse as they increasingly damage their body tissue over time. There is no actual way to prevent the damage from occurring as it is very aggressive in most of the children who show signs of the illness.

Types of Epidermolysis Bullosa:- (1) Epidermolysis bullosa simplex, (2) Junctional epidermolysis bullosa, (3) Dystrophic epidermolysis bullosa, (4) Hemidesmosomal epidermolysis bullosa.

Epidermolysis bullosa encompasses a group of otherwise heterogeneous diseases mainly characterized by the presence of extremely brittle skin and recurrent formation of blister which consequences from minor mechanical friction or trauma. It is the prototypic mechanobullous illness. This condition is not contagious. There is no therapy for EB. Management, hence, has to be tailored to the severity and extent of skin involvement and consists of supportive skin care, accessory care for other organ systems, and systemic therapies for complications.

Causes of Epidermolysis Bullosa

Some causes & risk factors of Epidermolysis Bullosa are as follows:

  • The disease consequences when skin layers different after minor trauma.
  • Infection of open lesions and sores.

Symptoms of Epidermolysis Bullosa

Symptoms depend on the type of epidermolysis bullosa, but can include :-

  • Blistering present at birth.
  • Nail loss other deformed nails.
  • Blistering around the eyes and nose.
  • Dental abnormalities such as tooth decay.
  • Alopecia (hair loss).

Traetment of Epidermolysis Bullosa

  • Treatment includes the application of appropriate non-adherent dressings to aid wound healing and prevent further injure and infections.
  • Gene therapy: The goal is to deliver genes targeted to restore normal protein production so that this disease is control.
  • Proper nutrition is also significant.
  • A topical antibiotic, such as bacitracin, mupirocin, other sulfadiazine, should be regularly applied.

 

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